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Ionic Liquids In Pharmaceutical And Biomedical Applications: A Review

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The present review focuses on the use of ILs in the pharmaceutical field, covering their multiple applications from pharmaceutical synthesis to drug delivery.Ionic liquids (ILs) have been used as solvents or materials, or both, in many applications, including pharmaceutics and medicine due to their exceptional properties consisting of . The challenges and future perspectives in the developments and applications of IL-based nanohybrids .The active pharmaceutical ingredient (API) solubility is critical for their bioavailability, dosing precision, stability, and overall efficacy. Ionic liquids (ILs) are pairs of ions in the liquid form synthesized at temperatures below 100 °C that meet specific demands of processes, rep 2024 Green Chemistry Reviews Ionic liquids (ILs) are, generally, salts containing poorly coordinated anions and cations at room temperature (RT) or below 100 °C.Melanoma is one of the most aggressive forms of skin cancer, which is characterized by metastasis and poor prognosis due to the limited effectiveness of .It is followed by the discussion on the application of ionic liquids in different biomedical domain like antimicrobial activity, anticancer activity and ionic liquid in drug delivery system or as active pharmaceutical ingredients.Marine resources have considerable potential to develop high-value materials for applications in different fields, namely pharmaceutical, environmental, and biomedical.Notably, the potential pharmaceutical applications of cellulosic biomass obtained from different sources have been discussed.108055 Corpus ID: 253272470; Ionic liquids as protein stabilizers for biological and biomedical applications: A review.Nowadays, the search of industrial applications of ionic liquids has boosted the design of biocompatible options, even bearing pharmaceutical and biological properties [3, 4], in line with the .This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active .The review highlights the recent advancement and further applications of ionic liquids to deliver drugs in the pharmaceutical and biomedical fields. Forming eutectic mixtures .In recent years, research on ions and ionic interactions in solution has become a leading scientific direction, and this advance has been especially pronounced in the field of ionic liquids, particularly coupled with the studies on their toxicity and biological activity.

Schematic representation of applications of ionic liquids. | Download ...

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Structure and Applications of Pectin in Food, Biomedical, and

Agarose, a polysaccharide derived from marine red algae, plays a vital role in biomedical applications because of its reversible temperature-sensitive gelling behavior, excellent mechanical properties, and high biological activity. ILs promote the generation of various nanohybrids that exhibit multiple functions a Journal of Materials .In recent years, astaxanthin as a natural substance has received widespread attention for its potential to replace traditional synthetic antioxidants and because its .

Surface-Active Ionic Liquids for Medical and Pharmaceutical Applications

This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active pharmaceutical ingredients, delivery of pharmaceuticals through biological barriers, stabilization of proteins and other nucleic acids, antibacterial agents, and development of new biosensors.

Pharmaceutics | Free Full-Text | Ionic Liquids in Pharmaceutical and ...

This review discusses the structure of keratin, its classification and its properties.The unique properties of ionic liquids (ILs), such as structural tunability, good solubility, chemical/thermal stability, favorable biocompatibility, and simplicity of preparation, have led to a wide range of applications in the pharmaceutical and biomedical fields.This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active pharmaceutical ingredients, delivery of .In the subsequent sections of this paper, we have addressed the pharmaceutical and biomedical applications of ionic liquids, respectively. Natural deep eutectic solvents (NaDES) represent a new generation of green, non-flammable solvents, useful as an efficient alternative to the well-known ionic liquids.There is a growing increase in research on pectins, which are becoming increasingly significant and widespread for different applications in the food and pharmaceutical industries and biomedical applications .Ionic liquids (ILs) are pairs of ions in the liquid form synthesized at temperatures below 100 °C that meet specific demands of processes, replacing organic solvents that are harmful .This review focuses on the application of IL methodologies to solve critical pharmaceutical problems, in particular, the low solubility and thus bioavailability of .}, author={Nathalia Vieira Ver{\’i}ssimo and Filipa A. The most relevant research conducted up to date is presented and discussed, together with a critical analysis of the most significant IL-based strategies in order to improve the . The potential of ionic liquid conjugates consisting protein or carbohydrates are also discussed.This review article focuses on advanced applications of ILs in the drug delivery, biosensing, biotechnology, and cosmetics to enhance the shelf-life of products .The potential applications of ionic liquids in the biomedical arena, including regenerative medicine, biosensing, and drug/biomolecule delivery, are presented to stimulate the scientific community to further improve the antimicrobial efficacy of ionsic liquids. Finally, the polymeric .Millions of tons of solvents are consumed annually in various industrial sectors, such as pharmaceuticals, chemical synthesis, textiles, coatings, paints, and others.This review presents a comprehensive survey on the utilization of ILs in the biomedical field. This paper aims to engage pharmaceutical and biomedical scientists to full understand PILs and accelerate the progress from laboratory research to industrialization. In the last years, ionic .

Ionic liquids: a state of the art for biomedical applications

Detailed parameters that affect the toxicity of these materials are presented.This paper presents a systematic and concise analysis of the recent advancements and further applications of ILs in the pharmaceutical field from the .

Biological Activity of Ionic Liquids and Their Application in ...

They can be easily prepared and exhibit unexpected solubilizing power for lipophilic molecules, although those of a hydrophilic nature are mostly used. However, some information on stability, ideal molecular weight, and interactions with other compounds still need to be . Ionic liquids (ILs) are pairs of ions in the liquid form synthesized at temperatures below 100 °C that meet specific demands of processes, rep 2024 Green Chemistry . Despite that, the lack of solubility of marine-derived polymers in water and common organic solvents could restrict their applications. It also covers various methods by which keratin is extracted like chemical hydrolysis, enzymatic and microbial treatment, dissolution in ionic liquids, microwave irradiation, steam explosion technique, and thermal hydrolysis or superheated process.This review focuses on the application of IL methodologies to solve critical pharmaceutical problems, in particular, the low solubility and thus bioavailability of pharmaceutical . View full-text Discover the world’s researchIn this review, we examine recent developments in the potential interplay between AMYs and AMPs, as well as their pathological implications for both infectious .Numerous compounds present in the ocean are contributing to the development of the biomedical field.

Ionic Liquids in Pharmaceutical and Biomedical Applications

From Synthesis to Functionality: Tailored Ionic Liquid-Based

Herein, we report an efficient and facile strategy for the preparation of imidazolium-based ionic liquid (IL) monomers ([CnVIm][Br], n = 2, 4, 6, 8, 10, and 12) . It specifically emphasizes the diverse structures and properties of ILs .

Extraction and application of keratin from natural resources: a review

Ionic liquids can be used as (i) green solvents . The focus of these studies has clearly shifted from environmental dangers to feasible . As the application of ILs in biomedicine is a rapidly emerging field, there is still a need for systematic analyses and summaries to .

Application of ionic liquids in pharmaceuticals | PPT

The biological effects and mechanisms of interaction between ionic liquids and bacterial strains as well as mammalian cells are highlighted.Ionic liquids (ILs) are composed of asymmetric cationic and anionic moieties and are used as green solvents.The present review presents the state-of-the-art progress made in the studies of IL-based nanohybrids in terms of their classifications, structure characteristics, versatile functionalities and biomedical and pharmaceutical applications. @article{Verssimo2022IonicLA, title={Ionic liquids as protein stabilizers for biological and biomedical applications: A review.Dedicated attention is given to a novel active pharmaceutical ingredient-ionic liquid (API-IL) concept, which suggests using traditional drugs in the form of ionic . Excessive and unwarranted administration of antibiotics has invigorated the .Ionic liquids (ILs), due to their inherent structural tunability, outstanding miscibility behavior, and excellent electrochemical properties, have attracted significant research attention in the biomedical field. Their non-toxic nature, favorable biocompatibility and adjustable structure facilitate wide biomedical applications.

IJMS | Free Full-Text | The Role of Ionic Liquids in the Pharmaceutical ...

Here we reviewed the advances of PILs in the biomedical field in the past five years with a focus on applications in proteomics, drug delivery, and development.This review covers the technologies and strategies developed to design biocompatible ILs, focusing on the design of biocompatible IL-based drug formulations and delivery systems, and discusses the advantages of these ILs in pharmaceutical and biomedical applications.The review gives a detailed insight into the recent literature on ionic liquid-based topical formulations like ionic liquid-based emulsions, active pharmaceutical ingredient-ionic liquids, ionic liquid-based bacterial cellulose membranes, topical small interfering RNA (siRNA) delivery, and ionogels as a possible solutions for overcoming the .Fundamental importance of ionic interactions in the liquid phase: A review of recent studies of ionic liquids in biomedical and pharmaceutical applications Journal of Molecular Liquids 10.The prominent aim of this paper is to review the applications of ILs in disparate pharmaceutical approaches such as the preparation of drug nanocarriers (as .This review focuses on the applications of ionic liquids in the pharmaceutical and biomedical fields.This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active pharmaceutical ingredients, delivery of pharmaceuticals through biological barriers, stabilization of proteins and other nucleic acids, antibacterial agents, and development of new biosensors .The present review provides a synopsis on the antimicrobial activity of ionic liquid-based materials. In recent years, research on ions and ionic interactions in solution has become a leading scientific direction, and this advance has been especially .The use of ionic liquids and deep eutectic solvents in biomedical applications has grown dramatically in recent years due to their unique properties and their inherent tunability.Ionic liquids (ILs) have been extensively used in drug formulation and delivery as designer solvents and other components because of their inherent tunability .Abstract: The unique properties of ionic liquids (ILs), such as structural tunability, good solubility, chemical/thermal stability, favorable biocompatibility, and . Fruit peels are primarily composed .Cholinium-based ionic liquids are compounds increasingly studied in pharmaceutics and biomedicine to enhance bioavailability in drug delivery systems and . Furthermore, this review will provide guidance on . ILs can not only speed up the chemical reaction process, improve the yield, and reduce . BACKGROUND Ionic liquids (ILs) are ionic compounds with highly tunable and remarkable properties .

Ionic liquids in pharmaceutical applications

This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active .Ionic liquids possess exceptional potential in field of medicine, biology and chemistry and are an important candidate in multitude of domains such as extraction, synthesis, analytics, catalysis, biotechnology, therapeutics as well as pharmaceutical sciences.The unique properties of ionic liquids (ILs), such as structural tunability, good solubility, chemical/thermal stability, favorable biocompatibility, and simplicity of . The potential applications of ionic liquids .